urokinase receptor造句

• The Somatomedin B domain interacts with the urokinase receptor, and this interaction has been implicated in cell migration and signal transduction.
• High plasma levels of both PAI-1 and the urokinase receptor have been shown to correlate with a negative prognosis for cancer patients.
• The SMB domain of vitronectin has been demonstrated to interact with both the urokinase receptor and the plasminogen activator inhibitor-1 ( PAI-1 ) and the conserved cysteines of the NPP1 somatomedin B-like domain have been shown to mediate homodimerization.
• ALX / FPR is a promiscuous ( i . e . interacting with diverse ligands ) receptor that binds and is activated by other ligands including : "'a ) "'various N-formyl oligopeptides that, like FMLP, are either released by microbes and mitochondria or are analogs of those released by microbes and mitochondria; "'b ) "'microbe-derived non-formyl oligopeptides; "'c ) "'certain polypeptides that are associated with the development of chronic amyloidosis and / or inflammation including Serum amyloid A ( SAA ) proteins ), a 42-amino acid peptide form Amyloid beta termed A?42, Humanin, and a cleaved soluble fragment ( amino acids 274-388 ) from the Urokinase receptor; and "'d ) "'other SPMs including Resolvins RvD1, RvD2, RvD5, AT-RvD1, and RvD3 ( see specialized pro-resolving mediators ).